Clinical research brain scan depression treatment. Psilocybin Therapy for Depression: What the Clinical Trials Actually Show From the first open-label feasibility studies in 2016 to two Phase 3 successes announced in 2025 and 2026, the clinical evidence for psilocybin in depression has moved faster than almost any psychiatric treatment in modern history. Here is what the research actually shows — and what remains genuinely uncertain. Category: Research and Microdosing |...

The Science of Psilocybe Mushrooms A science-forward guide to what peer-reviewed research actually shows about psilocybe mushrooms research, neuroplasticity, therapeutic trials, and microdosing — and why Canada is at the centre of the conversation. Category: Research and Microdosing | /7-research-and-microdosing Type: Pillar Article | /pillar-article Keywords: psilocybe mushrooms, psilocybin research, microdosing research, neuroplasticity, fungal biology, mycology science,

Mapping the mind's response. What Psilocybin Actually Does to the Human Brain: New Research Reveals Measurable Changes After a Single Dose A landmark 2026 study published in Nature Communications used EEG and MRI to track what happens to the human brain in the hours, weeks, and months after a first high-dose psilocybin experience. The findings are the clearest evidence yet that psilocybin produces real, measurable neurological changes — not just subjective ones. Category: R