Psilocybe cubensis Strain Guide — Mushroom Genetics & Strains | Spores Lab Canada Every cultivation outcome — colonization speed, flush consistency, contamination rate, fruiting body quality — is shaped by decisions made before a single grain jar goes into the pressure cooker. Some of those decisions are about substrate and technique. But the most foundational decision, and the one with the longest downstream consequences, is genetics: which strain you start with, and what